current research


2nef 5C8Q 2M65


398. Jung J, Byeon IL, Ahn J, Concel J, Gronenborn AM. 1H, 15N and 13C assignments of the dimeric C-terminal domain of HIV-1 capsid protein. Biomol NMR Assign 4(1): 21-23 (2010) PMC3448961.

399. Byeon IL, Meng X, Jung J, Zhao G, Yang R, Ahn J, Shi J, Concel J, Aiken C, Zhang P, Gronenborn AM. Structural convergence between cryoEM and NMR reveals novel intersubunit interactions critical for HIV-1 capsid function. Cell 139: 780–790 (2009) PMC2782912.

400. Matei E, Zheng A, Furey W, Rose J, Aiken C, Gronenborn AM. Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization. J Biol Chem 285: 13057-13065 (2010) PMC2857066.

401. HanY, Ahn J, Concel J, Byeon IL, Gronenborn AM, Yang J, Polenova T. Solid-state NMR studies of HIV-1 capsid protein assemblies. J Am Chem Soc 132: 1976-1987 (2010) PMC2829833.

402. Byeon IL, Dao KK, Jung J, Keen J, Leiros I, Døskeland SO, Martinez A, Gronenborn AM. Allosteric communication between cAMP binding sites in the RI subunit of PKA revealed by NMR. J Biol Chem 285: 14062-14070 (2010) PMC2859567.

403. Koharudin LMI, Liu H, DiMaio R, Kodali RB, Graham SH, Gronenborn AM. Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. Proc Natl Acad Sci USA 107: 6835–6840 (2010) PMC2872412.

404. Ahn J, Byeon I-J, Dharmasena S, Huber K, Concel J, Gronenborn AM, Sluis-Cremer N.  The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro.  Retrovirology 7: 40 (2010) PMC2873509.

405. Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon I-J, Jung J, Ahn J,  Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E,  Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G.  Small molecule  inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally  regulated switch in Nef action. Mol Biol Cell 19: 3279-92 (2010) PMC2947465.

406. Walsh JD, Meier K, Ishima R, Gronenborn AM. NMR studies on domain diffusion  and alignment in modular GB1 repeats. Biophys J 99: 2636-46 (2010) PMC2955504.

407. Ahn J, Vu T, Novince Z, Guerrero-Santoro J, Rapic-Otrin V, Gronenborn AM. HIV-1 Vpr loads Uracil DNA Glycosylase-2 onto DCAF1, a substrate recognition  subunit of a cullin 4A-RING E3 ubiquitin ligase for proteasome-dependent  degradation. J Biol Chem 285: 37333-41 (2010) PMC2988339.

408. Hou G, Paramasivam S, Byeon I-J, Gronenborn AM, Polenova T. Determination of  relative tensor orientations by γ-encoded chemical shift anisotropy/heteronuclear  dipolar coupling 3D NMR spectroscopy in biological solids. Phys Chem Chem Phys 12: 14873-83 (2010) PMC3160241.

409. Koharudin LM, Furey W, Gronenborn AM. Novel fold and carbohydrate specificity of the potent anti-HIV cyanobacterial lectin from oscillatoria agardhii. J Biol Chem 286: 1588-1597 (2011) PMC3020767.

410. Dao KK, Pey AL, Gjerde AU, Teigen K, Byeon IL, Døskeland SO, Gronenborn AM, Martinez A. The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation. PLoS ONE 6(3): e17602 (2011) PMC3048872.

411. Zhao G, Ke D, Vu T, Ahn J, Shah VB, Yang R, Aiken C, Charlton L M, Gronenborn AM,  Zhang P. Rhesus TRIM5α disrupts the HIV-1 capsid at the interhexamer interfaces. PLoS  Pathog  7(3): e1002009 (2011) PMC3063768.

412. Ahn J, Novince Z, Concel J, Byeon C, Makhov AM, Byeon IL, Zhang P, Gronenborn AM. The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1. Biochemistry 50: 37333-37341 (2011) PMC3072279.

413. Matei E, Louis JM, Jee J, Gronenborn AM. NMR solution structure of a Cyanovirin homolog from Wheat Head Blight Fungus. Proteins 79: 1538-1549 (2011) PMC3076533.

414. Jung J, Byeon IL, Ahn J, Gronenborn AM. Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.  Proteins 79: 1609-1622 (2011) PMC3076547.

415. Koharudin LMI, Viscomi AR, Montanini B, Kershaw MJ, Talbot NJ, Ottonello S, Gronenborn AM.  Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the Rice Blast Fungus Magnaporthe oryzae.  Structure 19(5): 662-674 (2011) PMC3094573.

416. Koharudin LM, Gronenborn AM. Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin. Structure 19: 1170-1181 (2011) PMC3154684.

417. Wang X, Matei E, Deng L, Ramström O, Gronenborn AM, Yan M. Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N. Chem Commun 47 (30): 8620-8622 (2011) PMC3800545.

418. Hou G, Yan S, Sun S, Han Y, Byeon I-J, Ahn J, Concel J, Samoson A, Gronenborn AM, Polenova T. Spin diffusion driven by R-symmetry sequences:  Applications to homonuclear correlation spectroscopy in MAS NMR of biological and organic solids.  J Am Chem Soc 133(11): 3943-3953 (2011) PMC314860.

419. Garrett DS, Gronenborn AM, Clore GM.  A short recollection on the paper entitled “A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams” by D.S. Garrett, R. Powers, A.M. Gronenborn and G.M. Clore [J. Magn. Reson. 95 (1991) 214-220]. J Magn Reson 213(2): 364-365 (2011).

420. Hou G, Byeon I-JL, Gronenborn AM, Polenova T.  1H-13C/1H-15N heteronuclear dipolar recoupling by R-symmetry sequences under fast magic angle spinning for dynamics analysis of biological and organic solids. J Am Chem Soc 133 (46): 18646-18655 (2011) PMC3218250.