current research


1bds 2rmm 2KOD


512. Nestor G, Ruda A, Anderson T, Oscarson S, Widmalm G, Gronenborn AM. (2021) A detailed picture of a protein-carbohydrate hydrogen-bonding network revealed by NMR and MD simulations. Glycobiology 31(4):508-518. PMID: 32902635. PMC8091458

513. Guseman AJ, Whitley MJ, González JJ, Rathi N, Ambarian M, Gronenborn AM. (2021) Assessing the structures and interactions of γD-Crystallin deamidation variants. Structure 9(3):284-291.e3. PMC7935750.

514. Perilla JR, Hadden-Perilla JA, Gronenborn AM, Polenova T. (2021) Integrative structural biology of HIV-1 capsid protein assemblies: combining experiment and computation. Curr Opin Virol. 48:57-64. PMID: 33901736; PMC8187302.

515. Guo C, Fritz MP, Struppe J, Wegner S, Stringer J, Sergeyev IV, Quinn CM, Gronenborn AM, Polenova T. (2021) Fast 19F Magic Angle Spinning NMR Crystallography for Structural Characterization of Fluorine-Containing Pharmaceutical Compounds. Anal Chem 93(23):8210-8218. PMID: 34080855.

516. Sergeyev IV, Quinn CM, Struppe J, Gronenborn A, Polenova T. (2021) Competing Transfer Pathways in Direct and Indirect Dynamic Nuclear Polarization MAS NMR Experiments on HIV-1 Capsid Assemblies: Implications for Sensitivity and Resolution. Magn Reson (Gott). 2021;2(1):239-249. PMID: 34136885; PMC8203495.

517. Quinn CM, Zadorozhnyi R, Struppe J, Sergeyev IV, Gronenborn AM, Polenova T. (2021) Fast 19F Magic-Angle Spinning Nuclear Magnetic Resonance for the Structural Characterization of Active Pharmaceutical Ingredients in Blockbuster Drugs. Anal Chem. 93(38):13029-13037. PMID: 34517697.

518. Baskaran K, Wilburn CW, Wedell JR, Koharudin LMI, Ulrich EL, Schuyler AD, Eghbalnia HR, Gronenborn AM, and Hoch JC. (2021) Anomalous amide proton chemical shifts as signatures of hydrogen bonding to aromatic sidechains. Magn Reson 2, 765–775.

519. Byeon IL, Calero G, Wu Y, Byeon CH, Jung J, DeLucia M, Zhou X, Weiss S, Ahn J, Hao C, Skowronski J, Gronenborn AM. (2021) Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A. Nat Commun. 2021 Nov 25;12(1):6864. PMID: 34824204.PMC8617076

520. Zadorozhnyi R, Sarkar S, Quinn CM, Zadrozny KK, Ganser-Pornillos BK, Pornillos O, Gronenborn AM, Polenova T. (2021) Determination of Histidine Protonation States in Proteins by Fast Magic Angle Spinning NMR. Front Mol Biosci. 8:767040. PMID: 34957215; PMC8703106.

521. Fuentes M, Srivastava S, Gronenborn AM, LaBaer J. (2021) A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2. Int J Mol Sci.23(1):53. PMID: 35008477; PMC8744954.

522. Gronenborn AM. (2022) Small, but powerful and attractive: 19F in biomolecular NMR. Structure 30(1):6-14. PMID: 34995480. PMC8797020

523. Zhu W, Guseman AJ, Bhinderwala F, Lu M, Su XC, Gronenborn AM. (2022) Visualizing Proteins in Mammalian Cells by 19F NMR spectroscopy. Angew Chem Int Ed Engl. 2022 Jun 7;61(23):e202201097. doi: 10.1002/anie.202201097. Epub 2022 Mar 30. PMID: 35278268; PMC9156538.

524. Yang DT, Gronenborn AM, Chong LT. Development and Validation of Fluorinated, Aromatic Amino Acid Parameters for Use with the AMBER ff15ipq Protein Force Field. J Phys Chem A. 2022 Apr 14;126(14):2286-2297. doi: 10.1021/acs.jpca.2c00255. Epub 2022 Mar 30. PMID: 35352936; PMC9014858.

525. Porat-Dahlerbruch G, Struppe J, Quinn CM, Gronenborn AM, Polenova T. (2022) Determination of accurate 19F chemical shift tensors with R-symmetry recoupling at high MAS frequencies (60-100 kHz). J Magn Reson. 2022 Jul;340:107227. doi: 10.1016/j.jmr.2022.107227. Epub 2022 Apr 26. PMID: 35568013.

526. Lu M, Toptygin D, Xiang Y, Shi Y, Schwieters CD, Lipinski EC, Ahn J, Byeon IL, Gronenborn AM. (2022) The magic of linking rings: Discovery of a unique photoinduced fluorescent protein crosslink. J Am Chem Soc.2022 Jun 22;144(24):10809-10816. doi: 10.1021/jacs.2c02054. Epub 2022 May 14. PMID: 35574633; PMC9233106

527. Gronenborn AM, Polenova T. Introduction: Biomolecular NMR Spectroscopy. Chem Rev. 2022 May 25;122(10):9265-9266. doi: 10.1021/acs.chemrev.2c00142. PMID: 35611522.

528. Sarkar S, Runge B, Russell RW, Movellan KT, Calero D, Zeinalilathori S, Quinn CM, Lu M, Calero G, Gronenborn AM, Polenova T. Atomic-resolution structure of SARS-CoV-2 nucleocapsid protein N-terminal domain. J Am Chem Soc. 2022 Jun 15;144(23):10543-10555. doi: 10.1021/jacs.2c03320. Epub 2022 May 31. PMID: 35638584. PMC9173677

529. Porat-Dahlerbruch G, Struppe J, Quinn CM, Gronenborn AM, Polenova T. 19F fast MAS (60-111 kHz) dipolar and scalar based correlation spectroscopy of organic molecules and pharmaceutical formulations. Solid State Nucl Magn Reson. 2022 Dec;122:101831. doi: 10.1016/j.ssnmr.2022.101831. Epub 2022 Sep 23. PMID: 36182713.

530. Zhang C, Guo C, Russell RW, Quinn CM, Li M, Williams JC, Gronenborn AM, Polenova T. Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation. Nat Commun. 2022 Nov 10;13(1):6795. doi: 10.1038/s41467-022-34026-w. PMID: 36357375; PMCID: PMC9649657.